Peanut Allergy

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This item of the newsletter really is in the form of a request.
We have a child who can and has had a severe reaction to nuts.
Anaphylaxis is a medical condition that manifests itself with an adverse reaction to particular foodstuffs and/or insect bites.
The school meals service is aware of the situation.
As a school we are now requesting that no packed lunch pupil bring peanuts (or indeed any nuts) in their packed lunch.

Johns Hopkins Magazine

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A recent study in Feinberg's lab that compared massive stretches of human DNA and mouse showed many similar genes: "We expected that," says Feinberg.
What was surprising, however, was how little humans and mice hold in common in the DNA outside of genes--the so-called "junk" DNA whose role, so far, remains one of science's mysteries.
For the nearly one in 200 children and adults with peanut allergy, avoiding peanut products becomes a life-long mission.
You can almost hear their little ratty chuckles-- "gotcha!"--through-out the night.
But not "autistic" rats, says Hopkins neuroscientist Mikhail Pletnikov.
To pinpoint what goes wrong in diseases such as autism and ADHD, illnesses that, current thought tells us, are surely developmental, Pletnikov and colleagues have come up with a rat model that resembles humans in the most telling ways.

ICOV1379

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Anthelmintic product launched in Egypt 22 Antimicrobial peptides: therapeutic potential discussed 3 Efavirenz vs nevirapine in HIV infections 11 Nevirapine vs efavirenz in HIV infections 11 PEG interferon- -2b + ribavirin worth it in chronic hep C 6 Ribavirin + PEG interferon- -2b worth it in chronic hep C 6 Tipranavir overcomes HIV resistance to protease inhibitors 7 Varicella vaccine immunogenic in nephrotic children 14 TB: is DOTS-plus worth it in developing countries?

Vaccine for peanut allergy effective in mice

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NEW YORK (Reuters Health) - US researchers believe they are on the road to developing a safe and effective vaccine for the more than 1.5 million Americans with life-threatening peanut allergy.
The vaccine proved "very effective" in mice with a peanut allergy, Dr. Hugh A. Sampson, from Mount Sinai in New York, said during a telebriefing Thursday.
"The highest dose gave markedly extended protection," according to Dr. Sampson.
The test, which relies on antibody differences between patients, could be commercially available within a few years, according to the report.
The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.

Are early exposures linked with childhood peanut allergy?

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Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood.
Peanut allergies are associated with intake of soy products in the first 2 years of life, a history of rashes over joints and skin creases (especially oozing, crusted ones), and use of skin creams containing peanut oil.
This portion includes data on exposure to soy products within the first 2 years of life, a history of rash over joints and skin creases, and a history of oozing, crusted rash.
The remaining interview data were collected retrospectively through a nested case-control design within the cohort.

Journal Watch Pediatrics and Adolescent Medicine - The Evolving Science of Peanut Allergy

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The apparent increase in cases of peanut allergy has led to renewed study of the allergy's etiology and treatment.
Use of creams containing peanut oil was also significantly related to allergy (91% of children with positive peanut allergyhad been exposed to such creams, vs. 53% of atopic controls and 59% of healthy controls).
In a double-blind, randomized treatment trial, 82 patients (age range, 13-59 years) with histories of immediate peanut hypersensitivity received weekly treatment with subcutaneous doses of 150, 300, or 450 mg of TNX-901 (a humanized IgG1 monoclonal antibody) or placebo for 4 weeks.
These findings suggest that parents should not give their children soy milk, soy formula, or creams containing peanut oil.

A Peanut Allergy May Go Away

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Some children who have a mild peanut allergy may outgrow it.
Researchers in London tested 120 children ages 2 through 9 who had had a mild reaction to peanuts at an earlier point in their life.
"These findings challenge the belief that every child who has a peanut allergy has it for life," says Hugh Sampson, M.D., chief of the division of pediatric allergy and immunology at Mount Sinai Medical Center, in New York City.
If your child has a mild peanut allergy, ask your doctor if it makes sense to retest him before he starts school.
"Because peanuts are found in many products, knowing your child is no longer bothered by them could set your mind at ease," says Dr. Sampson.

Peanut Allergy Awareness Posters

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Peanut allergy awareness posters perfect for child care centres, elementary schools and cafeterias.
Order one poster and receive a second poster free!
or order a pair (one of each) for the price of a single poster.
Both posters are 12" x 18" in full colour.
pair Canadian funds (one of each.) Now $12.95!
pair American funds (one of each.) Now $9.95

Children Might Outgrow Peanut Allergy

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A new study reveals that children's peanut allergies might not last forever, a finding that contrasts with what researchers previously thought.
In addition, occasionally eating peanuts could help children keep up a tolerance for the nut, said Dr. Robert Wood, pediatric allergy specialist at Johns Hopkins Children's Center, who conducted the study.
More than half had no reaction when they ate a peanut product.
David Reading, head of the U.K.'s Anaphylaxis Campaign, told the BBC parents of children should be aware of the new findings.
But he warned emergency medication should be accessible until the child has been tolerant for one to two years.

PEANUT ALLERGY

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Peanut allergy is a very serious and potentially lethal sensitivity about which the public has heard a great deal in the past two years.
The purpose of this Health Alert is to advise peanut - sensitive persons who are also asthmatic of the risks involved in using some commonly prescribed bronchodilator medications.
The only "rescue inhaler" reportedly without lecithin and thus appropriate for peanut-sensitive individuals is VENTOLIN metered dose inhaler, ordered as "brand medically necessary".
The only inhalation therapy solutions reportedly without lecithin are ATROVENT and XOPENEX.Serevent, Atrovent inhaler, Combivent inhaler, Proventil inhaler, Albuterol inhaler, and also Flovent (steroid) inhaler cannot be recommended, based on the above information.

Peanut Allergy May be Passed Through Breastmilk

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Nursing mothers who have a family history of peanut allergies may want to consider avoiding peanuts and foods that contain them while they are breastfeeding.
That initial exposure, which some researchers now say could have been through their mother's breastmilk, may have led them to be sensitized, leading to an allergic reaction later in childhood.
The women each ate 50 grams of dry roasted peanuts, then researchers tested their breastmilk at hourly intervals for peanut protein and the two major peanut allergens.
"That constitutes a potential route of unrecognized exposure of the breastfeeding infants to peanut protein and allergic sensitization to peanuts in the infants."

Science News Online - This Week - News Feature - 9/20/97

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After eating a meal with satay sauce in a Paris restaurant, a 22-year-old man who is allergic to peanuts suffers cardiac arrest, falls into a coma, and is diagnosed as brain dead.
The donor's pancreas and other kidney go to a 27-year-old woman, who also rebounds.
Three months later, however, the male recipient -- who has no previous allergy to peanuts -- breaks out in a rash after eating some of these legumes.
In earlier studies, transplanted bone marrow has been shown to transfer some allergies, apparently because bone marrow is rich in hematopoietic stem cells -- immature cells whose daughters grow into red and white blood cells.

Is Soya Milk Consumption Linked to Peanut Allergy?

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Is Soya Milk Consumption Linked to Peanut Allergy?
Researchers at the Univerity of Bristol are reporting a possible link between early childhood consumption of soya milk and peanut allergies.
Of the 49 infants in that sample who had peanut allergies, almost 25 percent hd consumed soya milk in their first two years of life.
Imperial College's Dr. Gideon Lack told the BBC, "These results suggest that senisitsation to peantu may possibly occur.
This is, however, obviously a small sample of children with peanut allergies and much more research needs to be done to determine if this is a real effect or simply a statistical artifact.

Commentary: Peanut allergy in-flight

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An unknown but probably significant number of airline passengers are allergic to peanuts.
Because peanuts are sometimes dispensed by flight attendants on commercial flights, there is public concern that passengers are at risk of an in-flight allergic reaction.
Although there is little in the medical literature to substantiate this concern, there are anecdotal cases of inflight allergic reactions to peanuts from ingestion, dermal contact, and inhalation of airborne peanut particles.
Consequently, there are several options among which the airlines must choose in order to satisfy passenger concerns.
Information on subscribing, and on obtaining copies of an article or of an entire issue.

PeanutAllergySoyaFormula

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SMA Nutrition notes with interest a recent study published in the New England Journal of Medicine "Factors Associated with the Development of Peanut Allergy in Childhood" which suggests that the rise in peanut allergy in recent years may be linked to the use of skin creams containing peanut oil and the consumption of soya milk or soya infant formula.
The research hypothesises that because soya beans and peanuts belong to the legume family, there may be common protein allergies which may cause cross sensitisation in those who are at risk of developing peanut allergy.
Reassuringly the research also stated that there is a low prevalence of clinical reactivity to soya in infants with peanut allergy and this is highlighted from the results of the study as only 1% of the total number of children who had consumed soya milk had peanut allergy.

03.03.11 - Drug can limit peanut allergy, easing big fear.

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Monthly injections of the drug TNX-901 can protect people allergic to peanuts from experiencing a life-threatening reaction when they accidentally consume a small number of peanuts.
Kolata G. Drug can limit peanut allergy, easing big fear.
Lack G, Fox D, Northstone K, Golding J, for the Avon Longitudinal Study of Parents and Children Study Team.
Factors associated with the development of peanut allergy in childhood.
Leung DYM, Sampson HA, Yunginger JW, Burks AW, Schneider LC, Wortel CH, Davis FM, Hyun JD, Shanahan WR, for the TNX-901 Peanut Allergy Study Group.
Effect of anti-IgE therapy in patients with peanut allergy.
Merz B. Behind the research: Studying peanut anaphylaxis.

Interesting causes for peanut allergy identified, Cincinnati Childrens Hospital Medical Center

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The incidence of peanut allergy has continued to rise over the last several decades and now affects approximately 1.5 million people in the U.S. The cause for this epidemic is largely unknown.
Analysis of these 49 individuals as well as the 23 individuals with bona fide peanut allergy revealed very interesting associated findings.
Notably, cord blood analysis revealed no detectable IgE to peanut indicating in utero exposure was not likely to account for the sensitization.
Analysis of detailed interview data revealed that about 90% of individuals with peanut allergy were exposed to skin creams that contained peanut oil especially during the first six months of life.

Peanut allergy: where do we stand?

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If this is not your name, click here.
The latest on peanut allergy from the medical literature and related sources compiled by Dr. John Weisnagel.
Any question regarding a medical diagnosis, treatment, referral, drug availability or pricing should be directed to either a licensed physician or to the product's manufacturer.
If you have any technical questions or other concerns about this site, feel free to contact us at webmaster@docguide.com.
All contents Copyright © 2000 P\S\L Consulting Group Inc.

Peanut Outgrow

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PEANUT ALLERGY: Peanut sensitivity is a common allergy in North America and because this allergy is often associated with anaphylactic reactions and because it is a common foodstuff, peanut sensitivity represents one of the most worrisome of allergic reactions.
Anaphylaxis is defined as a multisystem allergic reaction and in children is most threatening when the reaction involves the respiratory system (any of choking, stridor, coughing, wheezing).
A reaction to peanut is usually confirmed by a positive peanut skin test or RAST test (measurement of specific IgE antibody to peanut).
Nevertheless a positive skin test and/or RAST test to peanut does not automatically mean that there will be a clinical reaction but the larger the positive skin test or the higher the RAST test value, the more likely there will be a clinical reaction if peanut is consumed.

Peanut Allergy Experimental Drug

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People in the study could tolerate an average on nine peanuts without severe problems.
After the ownership issued gets sorted out, the drug must still go through the approval process in the U.S. and Canada, which can be a lengthy procedure.
Medical experts predict that the drug could cost as much as $10,000 US per year per patient.
Dr. Donald Y.M. Leung of the National Jewish Medical and Research Center in Denver headed the study which was presented at a meeting of the AAAAI (American Academy of Allergy Asthma & Immunology).
The study will be published in the New England Journal of Medicine this week.

Peanut Allergy In Children

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I am concerned about sending him to school as he has a severe peanut allergy.
PEDIATRICIAN DR.PAUL ANSWERS: Your question reminds me of the time I was in a meet the teacher meeting for my daughter, when she started grade 1, about 7 years ago.
I was shocked to see the reaction of some of the parents who felt this to be a great inconvenience.
Obviously the younger children are, the more likely that accidents will happen.
So I do believe that declaring a school or a day care "peanut free" is appropriate, and most parents will come to understand the necessity if the potential consequences are explained.

Health Minutes 19/3/2003 Causes of peanut allergy

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Peanut allergy can be induced by the tiniest amounts -- even traces on a knife from making a peanut butter sandwich.
The factors which were associated with peanut allergy were; drinking soy milk, having had a rash affecting the creases over joints, having a rash which oozed and crusted, and (interestingly) having used skin creams or lotions containing peanut oil in the past.
The first two factors - soy and the eczema type rashes - could just have indicated a child who already had allergic tendencies.
All this needs to be confirmed and more work done to see whether these findings can translate into prevention.

Some children may outgrow life-threatening peanut allergy, researchers find

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TORONTO (CP) - Some children who are allergic to peanut may actually outgrow the life-threatening allergy, some American researchers have reported.
Those who have low levels of peanut-specific antibodies circulating in their blood could then be given a "peanut challenge" under controlled circumstances to see if they are still allergic.
"Although we once thought peanut allergy was a life-long problem, we now believe certain children, namely those with low levels of allergy antibodies, may outgrow it," Dr. Robert Wood, pediatric allergist and immunologist at Johns Hopkins Children's Center in Baltimore, said Thursday.
Wood, who was the senior author on the study, said based on the findings he now recommends that children with peanut allergy be retested every year or two.

Predicting Peanut Allergy Reactions

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Once a child has an allergic reaction to peanuts, she will, if exposed to peanuts again, almost certainly have additional reactions.
A retrospective study of 184 young people 4 to 20 years old, found that the severity of a previous reaction did not predict how severe the next reaction would be.
The number of body systems involved with a reaction generally increased with each subsequent episode.
About one-third of all first reactions involved more than one body system, increasing to half of second reactions and 60% of third reactions.
Children with a peanut allergy must carry an Epi-Pen at all times.

Welcome to Peanut Allergy Awareness

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E-mail us with your questions, tips or advice.
When little Jared begged his mother for peanut butter on toast, she had no idea that it would almost kill him.
Like one in 200 of the population Jared, aged five, suffers from a violent and potentially fatal allergy to peanuts.
Victims of the allergic condition can suffer anything from minor swelling to death when they come into contact with the proteins contained in peanuts.
It is a terrifying prospect for parents, who may only discover that their children are allergic when they suffer a bad reaction.
Peanut Allergy Awareness Copyright © 2000 [Peanut Allergy Awareness].

ArtsEdNet Archive for September 2000 Peanut allergy

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This week I was informed I have a student with an extreme allergy to peanuts.
This allergy is such that if the students even touches a napkin that had a peanut on it or the table under the napkin the reaction will occur.
It is so sensitive that anything or anyone that has come near a peanut or oil must be thoroughly washed to remove even the most minute traces of it.
I was told that the student could have a fatal reaction within 30 seconds!
Does anyone know how I could find out more about the ingredients in our art materials?

Peanut allergy breakthrough - smh.com.au

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Researchers have developed the first drug that can protect people who are allergic to peanuts the leading cause of all allergy deaths.
The monthly injections are not a cure.
But doctors believe the still-experimental drug should let people avoid severe complications if they unknowingly eat one or two peanuts, the typical accidental exposure.
"Basically, we would not be seeing people in the emergency room or the morgue from peanut accidents," said Dr S. Allan Bock, an allergist who was not part of the study.
Babies whose rashes or eczema were soothed by such creams were more likely to become allergic to peanuts than those whose creams did not include peanut oil, said Dr Gideon Lack of St Mary's Hospital at Imperial College in London.

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