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Background and Objectives: A laser with a wavelength in the
mid-IR range targeting the depth in skin where sebaceous glands are
located in combination with cryogen spray cooling was evaluated for
treatment of acne. A clinical study for the treatment of acne on backs
of human males was also conducted. Conclusions: The studies reported
here demonstrate the feasibility of treating acne using a photothermal
approach with a mid-IR laser and cryogen cooling. While the highest
incidence of acne occurs between the ages of 15 and 18 years in both
males and females, acne can begin at virtually any age and occasi-onally
persist into adulthood. Acne is a disease of the pilosebaceous unit
of the skin wherein there is an inflammatory reaction in the
oil-producing follicle [3]. The basic lesion of acne is the comedo,
an enlargement of the sebaceous follicle. Despite this return to the
pre-treatment sebum level, many patients remain clear of acne. The
mechanism of treatment with blue light ... http://www.candelalaser.com/Smoothbeam2/acne_ross_article.pdf
Antibiotic resistance can be an unwelcome side-effect of
acne treatment Evidence that topical and oral antibiotic treatment
of acne is increasing the selective pressure for drug resistance
in important hospital pathogens was reported at a seminar held by
the UK Acne Support Group on Jan 28 at the House of Commons, London,
UK. Since 1991, Anne Eady and her medical colleagues at the Skin
Research Centre at the University of Leeds, UK, have routinely taken
skin swabs from all patients with acne attending dermatology clinics.
So far, they have screened 3201 patients--by 1997, 65% carried antibiotic-resistant
Propionibacterium acnes. Starting in July this year, 1200 patients
receiving antibiotics for acne will be recruited in Leeds and Nottingham
in a study funded by the National Health Service with the aim of
drawing up national guidelines on the use of antibiotics in acne.
Eady stressed the importance of getting patients with acne to use
benzoyl peroxide when being treated with ...
These include acne, being very hairy, putting on weight, having
too few or no periods and fertility problems. You may have this if
you have polycystic ovaries plus one or more of the following: acne
excessive hair, particularly on the face, chest or tummy male-pattern
baldness (going bald like middle-aged men) having too few, irregular
periods or no periods at all being very overweight fertility problems
For example, as women get near the menopause, acne may clear up but
hairiness might get worse. Women with the syndrome often first consult
their GP in their late teens or early twenties with problems like
persistent acne or excessive hairiness, or because they have too few,
irregular periods or none at all. Hairiness and acne If you have acne
caused by PCOS, lotions and creams available without a prescription
may not help. The excessive hairiness and acne with PCOS are caused
by the ovaries producing more testosterone than normal. Whatever treatment
your doctor suggests, ... http://www.nelh.nhs.uk/treatmentnotes/12%20PCOS.pdf
Acne Treatment Modality versatile device for acne phototherapy.
Clearly, acne treatment (currently pending FDA clear-ance) is an exciting
new application of this device, which combines proprietary light-and-heat
energy (LHE) technology. "I like the fact that the SkinStation can
treat acne vulgaris, without the use of any medica-tion," said William
Brender, M.D., a plastic sur-geon in private practice in Glens Falls,
N.Y. The recommended treatment protocol for acne is twice a week for
four weeks. However, "if there is incomplete resolution of the acne,
I may perform two more sessions or a second treatment cycle," Dr.
Brender noted. We now have another modality to use while dealing with
the grow-ing antibiotic resistance of acne," said Barry Ginsburg,
M.D., a der-matologist in private practice in Birmingham, Ala. " continued
on page 4 Acne Feature on page 26 22 New Acne Tx Approaches.......
http://www.miinews.com/pdf/abgcover_0903.pdf
Acne Treatment At the recent American Academy of Dermatology
annual meeting in San Francisco, Palomar Medical Technologies (Burlington,
Mass.) introduced the LuxVT handpiece for the reduction of acne (not
yet cleared in the U.S.) and pigmented lesions. The LuxV is used with
the Palomar MediLuxT and EsteLuxT Pulsed Light Systems, and is the
first Lux handpiece designed for acne treatment. "A practical and
effective light treatment for acne in the presence of pharma-ceutical
and device-based treatments must meet certain performance criteria,"
said David B. Vasily, M.D., director of Aesthetica Cosmetic and Laser
Center in Bethlehem, Penn. acne remedies." While conducting clinical
trials, Dr. Vasily found that the LuxV significantly reduced his patients'
acne. All of the patients enrolled in the trials had suffered from
facial refractory acne for a number of years and had used conventional
topi-cal and/or oral medications, such as Accutane, Benzamycin, Tazorac,
Brevoxyl, ... http://www.miinews.com/pdf/abgcover_0703-1.pdf
For patients with darker skin types, the Nd:YAG laser is the
most ad-vanced technology available for the removal of unwanted hair.
Smoothbeam The Smoothbeam laser is used to treat fine lines
and wrinkles, acne, acne scars and oily skin. This laser not only
stimulates the production of collagen in the skin, but has a beneficial
effect on the sebaceous glands. Using a specific wavelength
of light, this system is used in a regular fashion to control acne
breakouts. Photodynamic Therapy(PDT) Photodynamic therapy is a state
of the art approach to skin rejuvenation and acne treatment. Intensive
Acne Program Using a combination of revolutionary laser technologies,
including the Smoothbeam, Vbeam and Blue U as well as aesthetic treatments
and Photodynamic Therapy, our physicians will design an individualized,
state of the art acne treatment program specific to your needs.
Our treatment regimens have proven to be quite effective in bringing
... http://www.reflectionscenter.com/reflections_menu.pdf
Acne is the most common skin condition in the United States,
Although there are several types of acne, this article will discuss
only the most p revalent type, called acne vulgaris or common acne.
Acne Defined These units of hair, follicle, and sebaceous gland are
called pilosebaceous units, and four factors affecting them con-tribute
to acne: Acne doesn't discriminate; people of all races and ages get
it. More than eight out of every 10 people aged 12 to 24 years develop
acne, which o rdinarily--but not always--goes away when they are in
their 30s. Acne may worsen the week before a menstrual period, probably
due to hormonal changes. Scrubbing the skin and picking at or squeezing
blackheads or whiteheads can wors-en acne. Also, certain types of
cos-metics seem to aggravate acne. http://www.femalepatient.com/pdf/patpc_1104.pdf
Acne is characterized by the presence of non-inflammatory lesions
(comedones - blackheads and whiteheads) and/or inflammatory lesions
(papules, pustules and nodules) on the face, back, chest and shoulders.
Ask about the duration of acne, previous treatments used and their
effects (including those bought over-the-counter), any psychological
difficulties, and what the person's expectations are regarding treatment1.
Examine the areas of skin affected by acne, in particular the face,
back and chest. Note if the acne is mostly inflammatory or non-inflammatory
and grade it as mild, moderate or severe: Mild acne -- open and closed
comedones and some papules and pustules. Moderate acne -- more frequent
papules and pustules, often with mild scarring. Severe acne -- also
includes nodular abscesses, and leads to more extensive scarring.
Dispel common myths -- acne is not caused by bad hygiene, poor diet,
or lack of exercise, and is not infectious. NICE guidelines recommend
that people with ... http://www.prodigy.nhs.uk/quickreferenceguides/QR%20Acne%20vulgaris.pdf
Medications target the four stages of acne development: sebum
production, hyperkeratinization and obstruction of the pilosebaceous
follicle, Propionibacterium acnes infection, and inflammation. Oral
antibiotics are useful in moderate-to-severe acne and are particularly
helpful for acne on the chest and back, where topical treatment is
less likely to be effective. To treat acne effectively, the physician
needs to develop a logical and realistic regi-men, tailored to the
patient's needs, based on the pathophysiology of acne, and taking
into account the growing problem of antibiotic resistance. HOW ACNE
DEVELOPS Acne vulgaris is a disease of the pilosebaceous follicle.
It is due to four processes: Sebum production, stimulated by andro-gens
Hyperkeratinization, leading to obstruc-tion of the follicle Infection
with Propionibacterium acnes, an anaerobic diphtheroid bacterium Inflammation
of the follicle and surround-ing tissue, caused by enzymes produced
...
The obstruction of the gland openings causes the accumulation
of sebum, which is followed by ab-normal proliferation of the bacterial
population, predominantly propionibacterium acnes (P.acnes). Topical
acne medications are usually irritating to the skin and more than
40% of acne bacteria are insensitive to oral antibiotics. Although
solar or artificial UV light has a mild camouflage effect on acne,
its comedogenic and photoaging effects prevent its use in acne therapy.
Visible light in the blue range, or to a less extent in the red range,
induces a photo-destructive effect on propionibacterium acnes that
may take part in the decrease in acne severity during the summer.
This UV-safe acne photoclearing (APC) system is designed to operate
above the threshold necessary to destroy the acne bacteria and at
a rate that is quicker than the time needed for proliferation to occur.
The four patients, who did not show a significant change in P.acnes
levels, had a low baseline level ... http://www.aesthetic.lumenis.com/pdf/clearlight_app_notes.pdf
announced today results from two Phase 1 clinical trial studies
with its XMP.629 compound, which is being developed as a topical treatment
for mild to moderate acne. Results of the cumulative skin irritation
and absorption clinical trial studies show that the XMP.629 acetate
gel (0.1%) in healthy volunteers and acne patients causes no significant
skin irritation, lacks systemic absorption and shows a reduction in
lesion counts as early as two weeks after daily dosing. "Currently
available topical treatments for acne have numerous efficacy and safety
concerns that impact patient compliance. We look forward to seeing
more data from our controlled Phase II trial in mild to moderate acne
patients, which should be available in August of 2004." Data from
this single center, open-label absorption study show that the daily
topical application of 4 grams of the XMP.629 gel in fifteen patients
with moderate to very severe acne lacked measurable systemic absorption,
was well tolerated, ...
A: Being a teenager is tough enough without the relentless
acne that tends to plague pubescent teens. Unfortunately, acne strikes
more than 90 percent of teens and so there's a good chance most teenagers
- along with many adults - will have to endure the plight of acne.
What causes acne? Acne is linked to hormone levels, specifically,
male hormones, or androgens. People with acne don't necessarily have
more androgens than those with seemingly perfect skin, they just have
different tolerance levels. Recent studies have determined there is
no connection between diet and acne. While acne is hardly life threatening,
it should be treated seriously. - Corticosteroids (an anti-inflammatory)
may be injected by a dermatologist directly into severe inflamed acne
lesions to help the healing process The bottom line is that acne can
be cleared up. With the products available today, there is no reason
to endure acne or get acne scars. http://www.medcenterone.com/PDF/juneIMOcoverreduce.pdf
nnounced today the initiation of a Phase I clinical trial
with its XMP.629 compound, which is being developed as a topical treatment
for acne. In several preclinical studies, XMP.629 was found to be
a potent, topical agent against Propionibacterium acnes and other
related skin microorganisms associated with acne, demonstrating favorable
topical properties. Acne remains a widespread and frustrating disease
that drives an estimated 17 to 28 million Americans to seek some form
of treatment. "We're excited about moving XMP.629 into the clinic
and believe that there is a large, unmet medical need in the acne
patient population," said John L. Castello, XOMA's chairman, president
and chief executive officer. "Our XMP.629 compound has shown enduring
activity against strains of P. acnes resistant to antibiotics commonly
used to treat acne, as well as an acceptable topical profile." The
compound kills acne-causing bacteria. In preclinical studies, XOMA
...
We've watched adult and teenage acne sig-nificantly improve
without the use of medications. In just one procedure, you can be
rid of wrinkles, fat, acne, and possibly cellulite and stretch marks.
Acne Treatment Options New technology and medical advances are providing
more treatment options for individuals plagued with recurrent and
severe acne conditions. population who suffer from acne conditions
as well. The latest emerging technologies being used to treat acne
are Blue Light Laser and Thermage, and the results of these treatments
are coming without any adverse side effects or downtime! Blue light
laser works by killing the bacteria responsi-ble for acne. This Laser
therapy quite effectively decreases moderate, inflammator y acne in
just four to six weeks. Thermage treatments come with added benefits:
In addition to treating the acne, Thermage also works to minimize
the appearance of the scar-ring often associated with acne. http://www.lastingskinsolutions.com/documents/nl-2004-summer.pdf
Until recently most moderate to severe acne has been treated
by dermatologists with a combina-tion of antibiotics to kill the bacteria
and drying agents like Accutane and topical retinoids to control excess
oiliness. Recent research has poked some serious holes into two der-matological
staples for treating acne: One study that appeared in a February,
2004, edition of Journal of the American Medical Association pointed
to a strong association between long-term and/or frequent use of antibi-otics
and the incidence of breast Smoothbeam diode laser, made by Candela
Corp., became the first laser approved by the FDA to treat facial
acne. "Effectiveness of the acne treatments range from completely
clear skin to moderate improvement, depending on the type of acne,
lifestyle considerations and home care. The specific treatment for
acne works with four specific wavelengths--violet, green, red and
yellow--to destroy acne-causing bacteria. "We have added Max7 to our
Acne ... http://www.dayspamagazine.com/pdf/fac_prod_serv/ds0305all_clear.pdf
"My other presentations will describe the newest approaches
to the treatment of acne, photodamage and skin rejuvenation, including
the use of single and multiple lasers, such as Cynosure's pulse dye
and Nd:YAG lasers, and pulsed light source." " Our patients at the
Juva Center and MediSpa have seen excellent results with these new
state-of-the-art treatments and I am pleased to be presenting them
to this prestigious international audience," he added. " According
to the American Academy of Dermatology (AAD), more than 40 percent
of adolescents in their mid-teens have acne severe enough to require
treatment by a doctor. Thanks to the Internet, these kids and their
parents know about the available options and are requesting non-systemic
treatments along with, or as replacements for, medication," 10 Elizabeth
Drive Chelmsford, MA 01824 T 800.886.2966 - F 978-256-6556 www.cynosurelaser.com
said Marina Kamenakis, Cynosure Vice President of ... http://www.cynosurelaser.com/press_releases/Katz-EADV.pdf
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