Dizziness, drowsiness, headache, loss of appetite, constipation, nausea or stomach upset may occur the first several days as your body adjusts to the medication.

If any of these effects continue or become bothersome, inform your doctor.

Notify your doctor if you develop chest pain, a rapid pulse, skin rash, mental confusion, hallucinations or breathing trouble while taking this medication.

To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly.

Also limit your intake of alcoholic beverages which will aggravate these effects.

Use caution performing tasks requiring alertness if this medication causes you to feel drowsy.

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Precautions:

This medication should be used only if clearly needed during pregnancy.

Discuss the risks and benefits with your doctor.

Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Tell your doctor if you have any pre-existing kidney disease, heart disease, lung disease, asthma, emphysema, high blood pressure, an overactive thyroid, diabetes, depression or if you have a history of drug dependency.

Generic Name: Guaifenesin

Vicodin Tuss Syrup - Prescription

Kwelcof 5-100/5 ml Syrup - Prescription

Hydrocodone/Guaifenesin Syrup - Prescription

Hycosin Syrup - Prescription

Codotuss Syrup - Prescription

Cleartuss DH 5-100/5 ml Syrup - Prescription

Hycoclear Tuss Syrup - Prescription

Co-Tussin Syrup - Prescription

Vicoclear DH Syrup - Prescription

23284

Long-acting guaifenesin 600 mg is no longer a prescription product and is now conveniently available over-the-counter (OTC).
Kaiser Permanente physicians recommend that patients who were on prescription long-acting guaifenesin 600mg (original Humibid LA formulation) continue therapy by purchasing an OTC guaifenesin product.
Do NOT take prescription and OTC guaifenesin products at the SAME TIME.
Finish taking your remaining supply of prescription guaifenesin and then start using an OTC guaifenesin product instead.
Follow the directions on your new OTC guaifenesin product label carefully.

http://www.permanente.net/kaiser/pdf/23284.pdf
If you have any questions about your medications, please ask to speak with your pharmacist. guaifenesin, short-acting tablets.

mc1752

Louis Pasteur's discovery of spontaneous resolution of Mitscherlich's salt1,2 has had diverse and far going consequences.
Industrial applications of the phenomenon can be illustrated by the Merck process for antihypertensive methyldopa, the Haarmann and Reimer process for l-menthol, the Roussel--Uclaf process for chloroamphenicol, -amino acids.3 and industrial processes for artificial However, the potential of spontaneous resolution procedures is restrained by the necessity for a chiral compound subjected to resolution being a conglomerate.
The X-ray studies of single crystals picked up from racemic samples of o-substituted phenyloxy compounds 1--3 have revealed that they all belong to 'chiral' space groups P21, P212121 and P212121, respectively.

In this family, one enantiomer is more active in vivo than the other or a racemate.6 Because of their importance for medicinal chemistry, 3-aryloxy-propane-1,2-diols have received much attention from the synthetic standpoint. enantiomer, optical purity.

jakdxc04_guaifenesin_abs

James A. Kaduk, BP Chemicals, P.O. Box 3011 MC F-9, Naperville IL 60566 The crystal structure of the common expectorant guaifenesin, 3-(2-methoxyphenoxy)-1,2-propanediol (C10H14O4) was solved by applying Monte Carlo simulated annealing techniques to synchrotron powder data, and refined using the Rietveld method.
Initial structure solutions yielded an unreasonable conformation, and an unacceptable refinement.
Both hydroxyl groups act as hydrogen bond donors and acceptors, resulting in the formation of a 2-dimensional network of strong hydrogen bonds in the ac plane.
The solid state conformation is ~4 kcal/mole higher in energy than the minimum-energy conformation of an isolated molecule, but the formation of the hydrogen bonds results in an energy gain of ~100 kcal/mole.

http://www.dxcicdd.com/04/PDF/jakdxc04_guaifenesin_abs.pdf
Knowledge of the crystal structure permits quantitative phase analysis of guaifenesin-containing pharmaceuticals (such as Duratuss GP 120-1200) by the Rietveld method. conformation, energy gain.

Entex

A study was conducted in 30 healthy subjects to determine the bioavailability and pharmacokinetics of the Entex LA tablet under steady state conditions relative to corresponding immediate release pseudoephedrine hydrochloride and guaifenesin liquids.
Entex LA is contraindicated in individuals with known hypersensitivity to sympathomimetics, severe hypertension, or in patients receiving MAO inhibitors.
Sympathomimetic amines should be used with caution in patients with hypertension, diabetes mellitus, heart disease, peripheral vascular disease, increased intraocular pressure, hyperthyroidism, or prostatic hypertrophy.

http://www.purdue.ca/pdf/Entex.pdf
Tablets may be broken in half for ease of administration without affecting release of medication but should not be crushed or chewed prior to swallowing. Entex, mucus.