Vinblastine

used in the treatment of various cancers to slow or stop the growth of cancer cells

Side Effects:

Nausea, vomiting, and muscle pain are common side effects.

Not eating before your treatment may help relieve vomiting.

Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects.

In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting.

Temporary hair loss is another common side effect; normal hair growth should return after treatment has ended.

Precautions:

This medication can lower your body's ability to fight an infection.

Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills.

Avoid getting near people with the flu.

Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine.

Contraceptive (birth control) measures are recommended for use in men and women while taking this medication.

Avoid aspirin, alcohol, and citrus juice

Generic Name: Vinblastine Sulfate

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Vinblastine

Injection: Colourless solution for injection into the bloodstream.
Vinblastine is used for the treatment of cancers of the breast, bladder, testicles and lymphomas.
It is important to tell your doctor if you are taking the medication Phenytoin, or have chicken pox (or have recently been exposed to someone who has chickenpox), shingles, gout, kidney or liver disease.
Tell your chemotherapy nurse immediately if you feel pain or burning at injection site.
For more information on this medication, please call your Cancer Centre doctor or nurse at 387-9495, or the Hamilton Regional Cancer Centre Drug Information pharmacist at 575-6320.

Take prescribed medicine for nausea and vomiting. doctor, cold preparations.

Vinblastine1

How it is given: Your doctor will decide how much vinblastine you should have and when it will be given.
How it works Vinblastine slows or stops the growth of cancer cells in your body.
Common side effects Neutropenia (decrease in the number of white blood cells) A low number of white blood cells can make you more likely to get infections.
You may begin to notice these changes about a week after starting chemotherapy.
Less common side effects Neuromuscular and skeletal (muscles and bones) Vinblastine may cause jaw pain, bone pain and muscle weakness.

Mucositis (mouth sores) Chemotherapy can cause sores in the mouth and throat. doctor, avoid.

Vinblastine

Vinblastine is a drug used to treat cancer.
You may have redness, pain, warmth, or swelling at the IV site.
Photosensitivity means that you may become more sensitive to the effects of the sun, sun lamps, and tanning beds.
Genetic counseling is available to you to discuss the effect of this drug therapy on future pregnancies.
In addition, a genetic counselor can review the potential risks of problems in the fetus due to this medication if an exposure during pregnancy has occurred.

http://patienteducation.upmc.com/Pdf/Vinblastine.pdf

·Ask your doctor or nurse about medication that is available to help prevent or lessen nausea and vomiting. drug, Pittsburgh.

VINBLAST

Vinblastine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.
Hodgkin's disease Kaposi's sarcoma Non-Hodgkin's lymphoma Testicular cancer Oral absorption erratic Rapid and extensive binding to tissues and to formed elements of peripheral blood Cross blood brain barrier?
In hospitalized patients the urine may be alkalinized, by addition of sodium bicarbonate to the IV fluids, if tumour lysis is expected.
Severe jaw pain or parotid gland pain can occur within a few hours of the first dose of vinblastine.

http://www.cancercare.on.ca/pdfdrugs/VINBLAST.pdf

These gastrointestinal symptoms are seen especially when high doses are used (e.g.,>20 mg) and are rare with doses <10 mg. Toxicity and hematologic toxicity may be more severe in patients with severe cachexia, skin ulcers or marrow infiltration. vinblastine, myelosuppression.

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